SLU-PP-332 1000Mcg 30ct capsules

SLU-PP-332 is a research-grade compound categorized as an estrogen-related receptor (ERR) agonist, studied for its ability to influence energy metabolism, mitochondrial function, and metabolic health. This novel agent interacts primarily with ERRα and ERRγ, receptors known to regulate genes involved in fatty acid oxidation, glucose metabolism, and mitochondrial biogenesis—key factors in energy expenditure and oxidative metabolism.​

Key Research Insights
Peer-reviewed animal studies have demonstrated that SLU-PP-332 can substantially increase energy expenditure and fatty acid oxidation in models of diet-induced and genetic obesity, resulting in reduced fat mass and improved metabolic profiles without changes in food intake or physical activity. Further investigations highlight the compound’s role in enhancing skeletal muscle endurance and mitochondrial density, potentially elevating exercise tolerance through upregulated oxidative metabolism.​

SLU-PP-332 has also displayed positive effects on cardiac health. In preclinical models of heart failure, ERR activation by SLU-PP-332 improved cardiac mitochondrial ultrastructure, supported fatty acid metabolism, and enhanced cardiac function. Research continues to assess its potential applications for mitigating mitochondrial dysfunction associated with heart and neurodegenerative conditions, such as Parkinson’s disease, and in models of age-related decline.