KP500 (KPV) 500mcg 30ct tabs

KP500 (KPV) is a synthetic tripeptide extensively studied for its potent anti-inflammatory and antimicrobial properties in laboratory and preclinical research settings. As a C-terminal fragment of alpha-melanocyte stimulating hormone (α-MSH), KPV interacts with complex immune signaling pathways, showing promise for mediating inflammatory responses, promoting wound healing, and offering antimicrobial activity against pathogens such as Staphylococcus aureus and Candida albicans.​

Research Focus
KP500 (KPV) has demonstrated significant efficacy in animal models of inflammatory bowel disease (IBD) by reducing intestinal inflammation, histological evidence of infiltrates, and key inflammatory mediators—including TNF-alpha, NF-kappaB, and MAP kinases—without causing pigment changes commonly seen with full-length α-MSH analogs. Its effects appear selective for sites of active inflammation due to targeted transporter expression, making it highly relevant for studies of tissue-specific immune modulation and drug delivery mechanisms.​

Beyond the gastrointestinal tract, KPV’s impact on wound healing processes includes reducing excessive scar formation through modulation of collagen metabolism and suppressing pro-inflammatory cytokines such as IL-8. Its unique ability to combine anti-inflammatory and antimicrobial effects makes KPV a promising candidate for advancing research in tissue regeneration, infection control, and the study of complex immunomodulatory pathways.