Adipotide 5mg

Adipotide (FTPP) is a synthetic peptidomimetic compound designed to selectively target and induce apoptosis in the vasculature of white adipose tissue, making it a focal point of research in metabolic and obesity-related studies. This dual-domain peptide combines a homing sequence that specifically binds to prohibitin and annexin A2 receptors on endothelial cells supplying white fat with a proapoptotic sequence that triggers mitochondrial disruption and cell death. The targeted vascular collapse leads to ischemic injury and degradation of fat cells, providing a model for studying selective tissue ablation and adipose tissue remodeling.